mes jobs in San Diego

Senior Automation Engineer responsible for designing, integrating, and deploying scalable automation solutions across wet chemical processing lines, automated parts inspection systems, and CNC machining equipment in a high-tech manufacturing environment. Requires 10+ years of controls/automation engineering experience with hands-on expertise in PLC programming (WAGO, IDEC), HMI/SCADA development, motion control, and integration of vision systems (Cognex, Keyence).…See more Will manage cross-functional collaboration with operations, process engineering, quality, and IT teams; conduct vendor management and Factory Acceptance Testing; program control logic and communication protocols (EtherCAT, Ethernet/IP, Modbus/ModbusTCP); and ensure compliance with NEC, OSHA, NFPA, ANSI, and UL508A standards.

Staff Backend Engineer to design and build the core backend of Crucible, Firestorm's production planning and execution software. You will own system models representing production state (materials, inventory, resources, work), design for distributed operation across cloud, factory, and air-gapped deployments, and build durable integrations with PLM, ERP, quality, and optimization systems.…See more The role requires 8+ years shipping backend or distributed systems in production, strong relational data modeling and API design, and experience with complex state, workflows, and synchronization challenges. You'll partner on architecture, improve observability and reliability, and help raise the engineering bar across the team.

Senior Automation Engineer responsible for investigating equipment and process performance, optimizing designs and fixture systems, and managing capital planning for automation investments. Will lead end-to-end automation projects from requirements through FAT/SAT/deployment, specify and qualify manufacturing equipment, and drive the transfer of processes from R&D to production at scale.…See more Requires 8–12 years' experience in automated manufacturing systems, design of experiments, statistical analysis, and regulatory compliance (FDA 21 CFR Part 820, ISO 13485), with hands-on expertise in PLC/HMI, robotics, machine vision, and equipment integration.

Build and own the software layer connecting Fabric8Labs' electrochemical 3D printers to operators and business systems. Design PostgreSQL schemas and write Python backend services that interact with printers and edge devices in real time, build production dashboards and operator interfaces, and create integrations between shop-floor systems and ERP for work order flow, material tracking, and production reporting.…See more You'll work hands-on with hardware engineers, materials scientists, and operators to solve manufacturing workflow problems with direct, immediate feedback. The role requires 4+ years shipping production software, strong Python and PostgreSQL expertise, Linux proficiency, and JavaScript for UI—with a focus on understanding customer needs and building reliable, traceable systems.

Build end-to-end manufacturing software (MES, MRP, production planning, inventory, supply chain) for Crucible, a cloud and edge-deployed system that runs in factories, deployable microfactories, and air-gapped environments. Own features across data model, API, React frontend, and tests while partnering directly with manufacturing teams to translate operational problems into durable product capabilities.…See more Requires 5+ years of full-stack development with specific experience in manufacturing/production software domains and strong TypeScript, React, relational data modeling, and SQL skills.

Senior Full Stack Engineer owning end-to-end manufacturing software platform development across API, frontend, data model, and background jobs. You will design and evolve core domain models (work orders, engineering changes, effectivity, defect records) and ship production-quality features that technicians, supervisors, and quality teams rely on daily.…See more The role requires deep expertise in TypeScript, React, Node.js backends, and Postgres with strong proficiency in schema design, migrations, and transactional consistency. You'll partner with product, design, and manufacturing stakeholders to translate operational needs into maintainable software while raising standards on testing and observability.

Design, develop, and maintain software solutions that interface with coordinate measuring machines (CMMs) and metrology systems for advanced fabrication and inspection workflows. Integrate CMM equipment with internal databases, MES, PLM, and ERP systems; develop automation routines, reporting dashboards, and data visualization tools; and troubleshoot metrology software and system issues.…See more Requires 5–10 years of software engineering experience with hands-on CMM and metrology background, proficiency in C#, C++, Python, or similar languages, SQL/NoSQL database experience, and working knowledge of GD&T (Geometric Dimensioning and Tolerancing).

As Full Stack Engineer at Nucleus Biologics, you will develop and maintain software tools for scientists and manufacturing teams. Responsibilities include managing AWS infrastructure (EC2, RDS), maintaining Docker containers and Nginx, handling PostgreSQL schema and migrations, developing Python backends with FastAPI/Django/Flask, building React/TypeScript frontends, and resolving customer and internal issues.…See more You need strong production experience across the full stack: Python with modern web frameworks, React with current data-fetching patterns, PostgreSQL administration, and hands-on DevOps with Docker, Linux, and AWS.

This role requires a Teamcenter Integration Architect to design and implement large-scale PLM transformations, integrating Siemens Teamcenter with enterprise systems (ERP, MES, CAD/ECAD, data warehouses, and supplier portals). The architect will apply deep knowledge of Teamcenter integration frameworks (T4EA, T4S, T4O, Teamcenter Gateway, PLM XML, ITK) and web service protocols (SOA, REST, SOAP) to orchestrate complex data flows across engineering and business systems.…See more Experience with Oracle EBS/SAP integrations and CAD tools (Creo, Cadence, Mentor) is essential, particularly for part, BOM, and document synchronization patterns.

Lead technical support and implementation for SAP Manufacturing Execution (ME) and Manufacturing Integration and Intelligence (MII) systems in a multi-site manufacturing environment. Provide L2/L3 plant-floor application support, troubleshoot integration issues between SAP ME/MII and ERP modules (PP, EWM, QM, PM), and coordinate with cross-functional teams on system upgrades and lifecycle management.…See more Conduct gap analysis, evaluate MES solutions, lead implementation efforts, and ensure service delivery compliance with ITIL processes and SLAs.

Integration Architect for large-scale PLM transformation programs, specializing in Siemens Teamcenter integration with enterprise systems (ERP, MES, CAD/ECAD, data warehouses, supplier portals). Designs and validates scalable integration architectures, defining interface specifications, API designs, integration patterns (real-time, batch, event-driven), and manages coexistence between legacy and new systems.…See more Requires 4–6 years of hands-on experience with Teamcenter integration frameworks (T4EA, T4S, T4O, ITK, REST, SOAP, Webservices) and enterprise integrations (Oracle EBS/ERP, SAP). Works across vendor and geography boundaries, collaborating with business, IT, and offshore teams.

Senior Software Architect role leading technical strategy for complex manufacturing systems including additive manufacturing, machine control software, MES/ERP integrations, and fleet telemetry. Requires 8+ years of software engineering with 3+ years in architect/principal engineer roles, deep proficiency in C++, Rust, Python, C#, or Go, and hands-on experience with real-time systems, edge computing, motion control, and high-rate sensor data processing.…See more Responsibilities include architectural design, mentoring engineering teams, trade-off analyses, and cross-functional collaboration on New Product Introduction cycles, with expectation to operate credibly at both executive and hands-on technical levels.

This role requires architecting and implementing large-scale integrations between Siemens Teamcenter PLM and enterprise systems including ERP (Oracle, SAP), MES, CAD/ECAD tools, data warehouses, and supplier portals. The architect will design integration frameworks using Teamcenter-native tools (T4EA, T4S, T4O, Gateway) and standard protocols (REST, SOAP, WebServices, XML) to enable seamless data flows across PLM ecosystems.…See more Experience with enterprise data flows (parts, BOMs, suppliers, change orders, documents) and CAD system connectors (Creo, Cadence, Mentor) is essential. This is a hands-on technical leadership role in complex PLM transformation programs.

Design, develop, and maintain software solutions that interface with coordinate measuring machines (CMMs) and metrology systems in advanced fabrication and inspection environments. Integrate CMM equipment with internal databases, MES, PLM, and ERP systems to streamline data collection and reporting.…See more Develop automation routines, dashboards, and data visualization tools for measurement workflows, and troubleshoot CMM software and system issues. Work closely with manufacturing, quality, and engineering teams to translate GD&T requirements into repeatable software and measurement solutions, with 90% onsite presence required.