mes jobs in San Diego

As Full Stack Engineer at Nucleus Biologics, you will develop and maintain software tools for scientists and manufacturing teams. Responsibilities include managing AWS infrastructure (EC2, RDS), maintaining Docker containers and Nginx, handling PostgreSQL schema and migrations, developing Python backends with FastAPI/Django/Flask, building React/TypeScript frontends, and resolving customer and internal issues.…See more You need strong production experience across the full stack: Python with modern web frameworks, React with current data-fetching patterns, PostgreSQL administration, and hands-on DevOps with Docker, Linux, and AWS.

This role requires a Teamcenter Integration Architect to design and implement large-scale PLM transformations, integrating Siemens Teamcenter with enterprise systems (ERP, MES, CAD/ECAD, data warehouses, and supplier portals). The architect will apply deep knowledge of Teamcenter integration frameworks (T4EA, T4S, T4O, Teamcenter Gateway, PLM XML, ITK) and web service protocols (SOA, REST, SOAP) to orchestrate complex data flows across engineering and business systems.…See more Experience with Oracle EBS/SAP integrations and CAD tools (Creo, Cadence, Mentor) is essential, particularly for part, BOM, and document synchronization patterns.

Lead technical support and implementation for SAP Manufacturing Execution (ME) and Manufacturing Integration and Intelligence (MII) systems in a multi-site manufacturing environment. Provide L2/L3 plant-floor application support, troubleshoot integration issues between SAP ME/MII and ERP modules (PP, EWM, QM, PM), and coordinate with cross-functional teams on system upgrades and lifecycle management.…See more Conduct gap analysis, evaluate MES solutions, lead implementation efforts, and ensure service delivery compliance with ITIL processes and SLAs.

Integration Architect for large-scale PLM transformation programs, specializing in Siemens Teamcenter integration with enterprise systems (ERP, MES, CAD/ECAD, data warehouses, supplier portals). Designs and validates scalable integration architectures, defining interface specifications, API designs, integration patterns (real-time, batch, event-driven), and manages coexistence between legacy and new systems.…See more Requires 4–6 years of hands-on experience with Teamcenter integration frameworks (T4EA, T4S, T4O, ITK, REST, SOAP, Webservices) and enterprise integrations (Oracle EBS/ERP, SAP). Works across vendor and geography boundaries, collaborating with business, IT, and offshore teams.

Senior Software Architect role leading technical strategy for complex manufacturing systems including additive manufacturing, machine control software, MES/ERP integrations, and fleet telemetry. Requires 8+ years of software engineering with 3+ years in architect/principal engineer roles, deep proficiency in C++, Rust, Python, C#, or Go, and hands-on experience with real-time systems, edge computing, motion control, and high-rate sensor data processing.…See more Responsibilities include architectural design, mentoring engineering teams, trade-off analyses, and cross-functional collaboration on New Product Introduction cycles, with expectation to operate credibly at both executive and hands-on technical levels.

This role requires architecting and implementing large-scale integrations between Siemens Teamcenter PLM and enterprise systems including ERP (Oracle, SAP), MES, CAD/ECAD tools, data warehouses, and supplier portals. The architect will design integration frameworks using Teamcenter-native tools (T4EA, T4S, T4O, Gateway) and standard protocols (REST, SOAP, WebServices, XML) to enable seamless data flows across PLM ecosystems.…See more Experience with enterprise data flows (parts, BOMs, suppliers, change orders, documents) and CAD system connectors (Creo, Cadence, Mentor) is essential. This is a hands-on technical leadership role in complex PLM transformation programs.

Design, develop, and maintain software solutions that interface with coordinate measuring machines (CMMs) and metrology systems in advanced fabrication and inspection environments. Integrate CMM equipment with internal databases, MES, PLM, and ERP systems to streamline data collection and reporting.…See more Develop automation routines, dashboards, and data visualization tools for measurement workflows, and troubleshoot CMM software and system issues. Work closely with manufacturing, quality, and engineering teams to translate GD&T requirements into repeatable software and measurement solutions, with 90% onsite presence required.