systems-engineering jobs in San Diego

Cloud Engineer II supporting DevSecOps pipeline implementation, CI/CD workflows, automated security scanning, container deployment, and secure software delivery. Will assist with cybersecurity compliance activities including RMF documentation, Zero Trust alignment, vulnerability remediation, and audit-ready technical artifacts.…See more Requires 9+ years experience (or 7+ with Master's, or 4+ with PhD/JD), active Secret clearance, and ability to obtain TS/SCI. Must coordinate across architects, engineers, developers, cybersecurity teams, and government stakeholders to track tasks, troubleshoot issues, and communicate technical decisions and risks.

Senior Systems Engineer responsible for leading systems engineering activities on complex medical device and integrated products at BD. The role requires developing and executing reliability planning, driving cross-functional collaboration across engineering disciplines, investigating and resolving system performance issues, and mentoring junior engineers.…See more The position demands expertise in requirements management, system verification/validation, risk management (FMEA, hazard analysis), Design for Six Sigma methodologies, and model-based systems engineering, with 3-5+ years of relevant engineering experience and a strong technical background.

Sr. Systems Engineer I will translate complex technical findings into actionable recommendations for cross-functional teams (Quality, Manufacturing, Service Engineering, R&D, Regulatory, Leadership) in a medical device environment.…See more The role requires 4+ years of industrial systems engineering or product development experience, with strong preference for domain expertise in flow cytometry, cell analysis, signal processing, embedded systems, electronics, software, fluidics, optics, or assay reagents. Key responsibilities include executing system-level characterization, integration, and test procedures. A Bachelor's degree in engineering or related discipline is required; Master's or PhD preferred.

Sr. Systems Engineer supporting the Navy's Key Management project portfolio, responsible for leading system engineering, hardware, and software analysis to develop systems meeting customer requirements.…See more Will define and apply systems engineering processes, manage requirements (decomposition, allocation, verification, validation), develop system architecture and CONOPS, and produce comprehensive technical documentation including specifications, manuals, and design documents. Requires 8+ years of experience with model-based systems engineering, database management (MySQL, Oracle, SQL Server), Linux/UNIX, Agile methodologies, and DoD 8570-approved security certification. Will work at customer facilities up to 5 days/week, participating in customer meetings and technical interchange meetings.

Principal Systems Engineer leading full product development lifecycle for a Class II Medical Device, defining system architecture and engineering strategy across electrical, firmware, software, and manufacturing domains. Owns multidisciplinary systems end-to-end, establishing development processes (CI/CD, automated testing, version control), leading embedded hardware and firmware architectures, and ensuring FDA compliance and Design Controls adherence.…See more Serves as primary technical authority coordinating internal teams and external partners, conducting design/architecture reviews, supporting manufacturing scale-up, and mentoring cross-functional engineers. Requires 12+ years of multidisciplinary product development with demonstrated systems engineering expertise, regulated-industry experience, and technical leadership without direct authority.

Systems Engineer responsible for translating market and user needs into clear requirements across biology, hardware, and software subsystems at an early-stage cell-therapy manufacturing startup. Owns requirements management, interface control documentation, and system block diagrams to keep multiple engineering teams aligned during prototype development.…See more Leads verification, validation, and risk analysis planning; supports design reviews and regulatory compliance through design history file maintenance. Expects hands-on involvement in prototype assembly, testing, and cross-disciplinary problem-solving in a research-to-product transition environment.

This Systems Engineer role owns the requirements, interfaces, and risk management for an early-stage cell-therapy manufacturing platform spanning hardware, software, and biology. You will maintain requirements in dedicated tools, define and document interfaces between mechanical, electrical, fluidic, software, and cell-biology subsystems, support verification and validation planning, and coordinate across multiple engineering teams.…See more The role requires 5+ years at the intersection of biology, chemistry, and instrumentation, with hands-on lab experience and proven ability to run design reviews and resolve cross-team conflicts.

Senior Systems Engineer responsible for leading system integration planning, verification and validation strategy, and reliability engineering for complex medical devices or integrated systems at BD. Own cross-functional coordination across Reliability, Software, Electrical, Mechanical, Quality, Regulatory, Manufacturing, and Clinical teams while investigating system-level issues, managing technical risks (FMEA, hazard analysis), and mentoring junior engineers.…See more Develop requirements, drive design reviews, and apply Design for Six Sigma (DFSS) methodologies to enhance product quality and development efficiency from concept through commercialization.

The Senior Systems Engineer leads the full lifecycle of compute, camera, and radio systems—from requirements development through design, integration, testing, and qualification. You'll develop system architecture, define interfaces, conduct trade studies, and oversee verification and validation across hardware and software.…See more The role requires 8+ years of systems engineering experience, deep expertise in embedded systems (ARM, PowerPC, x86 processors), flight and ground software, RTOSes, and embedded protocols (SpaceWire, CameraLink, CAN, etc.), plus proficiency in C/C++, Python, and requirements management tools.

Senior Systems Engineer responsible for translating complex technical findings into actionable recommendations across Quality, Manufacturing, Service Engineering, R&D, Regulatory, and Leadership teams. Requires a bachelor's degree in engineering and 4+ years of industrial experience in systems engineering, product development, or sustaining roles.…See more Strongly preferred experience in flow cytometry or cell analysis domains (signal processing, embedded systems, electronics, software, fluidics, optics, assay reagents). Will execute system-level characterization, integration, and test procedures.

Staff Systems Engineer at BD will lead systems engineering efforts across complex medical device programs, driving reliability planning, product quality improvements, and cross-functional technical collaboration. The role requires deep expertise in requirements management, system architecture development, verification/validation, and risk management, with responsibility for mentoring junior systems engineers and championing MBSE and design methodologies.…See more The ideal candidate has 6–8+ years of systems engineering experience, preferably in regulated medical device development, and demonstrates exceptional ability to influence technical strategy across multiple disciplines without direct authority.

SAIC seeks a Systems Engineer to lead complex systems engineering activities across IT and engineering domains, including concept of operations, requirements definition, system architecture, validation/verification, and lifecycle cost analysis. The role demands translating customer requirements into comprehensive systems solutions while managing technical, schedule, and cost constraints through functional analysis, trade studies, and interface definition.…See more Responsibilities span infrastructure concerns (power, cooling, storage, monitoring, identity management, automation) and advanced technical problem-solving with independent judgment and strategic input. Requires a bachelor's degree plus 14+ years of experience (or master's plus 12 years, or PhD/JD plus 9 years) and an active TS/SCI clearance with polygraph.

The Systems Engineer applies systems engineering discipline to define, develop, integrate, and test complex in vitro diagnostic medical devices. Responsibilities include capturing user requirements, authoring system and subsystem requirements documentation, conducting hazard and risk analysis, managing configuration and change control, driving system integration and root-cause analysis, and coordinating with development, testing, clinical, and cross-functional teams.…See more The role requires a BS in engineering, 10+ years of industry experience, proven medical device development background, and proficiency in systems engineering methodologies including requirements decomposition, architecture, design reviews, and risk management.

Systems Engineer – Level II supporting systems engineering and continuous software sustainment in secure, mission-critical environments. The role encompasses architectural oversight, requirements traceability, system integration, operational support, vulnerability management, and technical-debt remediation across live production Linux and Windows enterprise infrastructure.…See more Requires 3+ years of systems engineering with Agile methodologies and 2+ years of recent enterprise server administration including VMware vSphere and AWS virtualized environments, with mandatory DISA STIG compliance expertise.

Senior Systems Engineer supporting the PMW 770 Link 16 program on mission-critical naval systems engineering activities. Responsibilities include providing technical program support, developing and reviewing Model-Based Systems Engineering artifacts, managing Engineering Change Requests, conducting technical reviews, drafting acquisition documentation, and coordinating systems test and evaluation.…See more Requires 7+ years of systems engineering experience, a bachelor's degree in engineering, and ability to obtain and maintain an Active DoD Secret clearance.

Lead complex medical device development programs for Dexcom's Stelo wearable glucose biosensor platform, driving cross-functional teams through research, verification, validation, and commercialization. Direct R&D, commercial, operations, quality, clinical, regulatory, and legal stakeholders; manage product roadmaps, timelines, and executive governance; resolve technical and business tradeoffs while mentoring team members.…See more Requires proven experience shipping novel wearable or connected medical devices with expertise across mechanical, electrical, systems, and mobile app engineering disciplines, plus familiarity with FDA and EU MDR regulatory pathways.

Lead the integration and testing of large, complex System-of-Systems (SoS) environments, with responsibility for developing test architectures aligned to operational requirements and capability-based engineering principles. Translate Operational Requirements Documents (ORDs) and Concepts of Operations (CONOPS) into test strategies for tactical communications and command-and-control architectures.…See more Requires a Master's degree in an Engineering field and an active Secret clearance.

This Systems Engineer role involves designing, integrating, implementing, and testing complex systems and systems-of-systems architectures in support of defense and tactical command-and-control missions. The candidate will define technical requirements, perform data analysis across multiple sources, develop technical documentation, and support cross-functional engineering teams.…See more The position requires 5–8 years of systems engineering or technical integration experience, with strong analytical and problem-solving skills, and an active Secret clearance.

Systems Engineer to integrate maritime sensors (aerostats, radars, cameras) with Navy command-and-control communications systems, creating unified operational pictures for allied partner navies. Responsibilities span requirements analysis, system design, hardware/software/network integration, site surveys, acceptance testing, and end-user training.…See more Requires 3+ years of systems engineering experience, hands-on network/hardware integration skills, and ability to travel internationally for site work and partner training.

Systems Engineer role focused on integrating maritime sensors (aerostats, radars, cameras) with Navy command-and-control systems to create unified operational pictures. You will own end-to-end system development from requirements and design through coding, testing, and field operations, working across hardware, networks, and software to make disparate systems interoperable.…See more Requires 3+ years of systems engineering experience, strong grasp of requirements analysis and system integration, hands-on networking and hardware integration, and a Bachelor's degree. Active Secret clearance and US citizenship required.

Level II Systems Engineer responsible for systems engineering, architecture, requirements traceability, and system integration in secure, DoD environments. Must maintain enterprise server administration expertise across Linux and Windows in virtualized environments (vSphere, AWS) with continuous monitoring and DISA STIG compliance.…See more Role requires meeting DoD 8140.451 System Administrator Intermediate Proficiency standards and eligibility for privileged/admin access. Work occurs within Agile frameworks (Scrum, Kanban, SAFe) supporting operational sustainment.

This Systems Engineer role at a medical device company requires decomposing regulatory and stakeholder requirements into testable system specifications, leading design reviews and verification/validation activities, and supporting risk management under FDA and ISO frameworks. The position demands 2+ years in a regulated medical device environment, with responsibility for traceability documentation, design history files, failure investigation, and CAPA activities.…See more Key competencies include FDA design controls, ISO 14971 risk management, human factors/usability per FDA guidance, and cross-functional communication of complex system interfaces to diverse audiences.

Staff Engineer on Qualcomm's CPU software architecture team responsible for designing, developing, and optimizing firmware and software for ARM-based SoCs across mobile, laptop, automotive, cloud, and server products. The role involves hardware-software co-design, system optimization, and participation in ARMv9 architecture enablement.…See more Responsibilities include writing and reviewing code, debugging, integration testing, and collaborating with hardware design teams to define software architecture across embedded and cloud-edge platforms.

Hardware Engineering Manager who establishes technical direction, engineering standards, and design practices across the hardware development lifecycle. The role balances organizational effectiveness, staffing, and execution health while partnering with Principal Engineers on discipline-level technical leadership.…See more Responsibilities span concept through production, including design reviews, technical risk management, electro-mechanical integration, military/industry standards compliance, and cross-functional collaboration with systems, software, production, and supply chain teams. Requires 8+ years developing complex hardware or electro-mechanical systems and proven experience leading engineering teams.

Lead a hardware engineering team to establish technical direction, engineering standards, and design practices across the full product lifecycle from concept through production. Own organizational effectiveness, staffing, and execution health while partnering with Principal Engineers on discipline-level technical leadership.…See more Drive hardware development excellence through electro-mechanical integration, design reviews, and continuous process improvement. Balance resources across customer programs, internal product development, and sustaining engineering while collaborating with Systems Engineering, Software, Production, Quality, and Supply Chain.