Jobs at Illumina

Staff HRIS Analyst responsible for configuring and supporting Workday Time Tracking, Absence, Benefits, and payroll integrations in a complex global organization. The role requires hands-on Workday configuration expertise, defining data mappings and reconciliation for payroll and benefits interfaces, leading end-to-end solution design, and planning releases with comprehensive testing strategies.…See more Responsibilities include diagnosing complex system and interface issues, leading HR technology initiatives from requirements through stabilization, and coaching team members on functional design and controls. The candidate must have 8+ years of related experience (or equivalent with advanced degree) with substantial Workday hands-on expertise and strong analytical and communication skills.

Staff-level embedded systems engineer leading hardware architecture and design decisions for complex genomic instrumentation. Owns hardware requirements, embedded system debugging, Design Verification Testing processes, and provides technical guidance to electrical engineering and firmware teams.…See more Requires 8+ years of embedded systems experience (or equivalent with advanced degree), expertise in PCB design, signal integrity, system integration, and hands-on troubleshooting of complex hardware-firmware interactions.

Sr. Director of Software Quality will build and lead Illumina's standalone Software Quality organization, establishing governance frameworks aligned with IEC 62304, ISO 13485, ISO 14971, and emerging AI Act requirements.…See more The role owns the Software Quality Management System across all software products, software-driven IVDs, and AI/ML-enabled diagnostics, embedding quality checkpoints throughout the product development lifecycle and post-market surveillance. Responsibilities include recruiting and developing a high-performing team, defining verification and validation standards, managing regulatory compliance for FDA, EU MDR/IVDR, and other global bodies, and serving as the subject-matter expert in regulatory inspections. The candidate must have deep hands-on expertise in IEC 62304, SaMD classification frameworks, cybersecurity in QMS (IEC 81001-5-1), and demonstrated experience building and leading software quality functions in regulated medical device environments.

Own the end-to-end product roadmap for DRAGEN Array, DesignStudio, and legacy array software, defining requirements based on customer needs and competitive landscape. Act as the voice of array software customers through Voice of Customer efforts, customer interviews, and advisory boards.…See more Drive go-to-market strategies for new launches and major releases, and translate complex technical capabilities into compelling narratives for enterprise buyers. Coordinate cross-functionally across Illumina's software portfolio to ensure array customers benefit from integrated platform capabilities.

Senior Staff Software Outbound Technical Product Manager at Illumina responsible for owning product positioning, go-to-market strategy, and customer relationships for a portfolio of genomics and life sciences SaaS products. The role requires translating complex technical capabilities into customer-centric narratives, leading voice-of-customer efforts, and partnering with Engineering, Sales, and Marketing to align roadmap decisions with commercial impact.…See more The ideal candidate has 12+ years of product management experience, deep knowledge of genomics analysis software and cloud platforms for genomics data analysis, familiarity with FDA/ISO:13485 regulated environments, and the ability to influence product strategy across multiple platforms and cross-functional teams.

Director-level product management role responsible for defining strategy, roadmap, and business planning for an integrated clinical solution spanning instrumentation, software, and assay content. The leader will manage a team of product managers while directly owning strategic initiatives, translating customer insights and market dynamics into product requirements, and driving cross-functional alignment across R&D, platforms, assay development, software, regulatory, and operations.…See more Success requires systems thinking, customer orientation, and the ability to guide tradeoff decisions for a complex multi-component offering in a matrixed environment.

Staff Data Engineer at Illumina seeking a senior individual contributor with 10+ years building and scaling data products on Databricks and Snowflake. The role spans end-to-end ownership of data pipelines across Supply Chain, Manufacturing, and Quality domains, requiring advanced Python, SQL, and data modeling skills with hands-on expertise in Spark, Delta Lake, dbt, and distributed systems design.…See more Responsibilities include designing medallion-architecture data products, embedding governance and data quality, adopting AI in analytics workflows, and mentoring a global engineering team. The candidate will set technical standards, lead architecture decisions, and communicate trade-offs across business, AI, and platform stakeholders.

Senior Software Engineer responsible for designing, building, and maintaining secure, fault-tolerant distributed systems for sequencing data transfer, storage, and management. Contribute to CI/CD pipelines, evaluate component designs, collaborate across software teams, and drive innovation while troubleshooting complex customer issues.…See more Required expertise in C# and .NET/Core with 5+ years of software development experience; strong background in distributed systems patterns, testing frameworks, and quality practices essential.

Senior Software Test Engineer at Illumina responsible for designing and executing comprehensive test strategies for complex instruments in a regulated medical device environment. The role requires troubleshooting across hardware and software boundaries, working hands-on with physical laboratory instruments, and managing defects and requirements through industry-standard platforms.…See more Candidates should have strong debugging and analytical skills, familiarity with embedded systems and communication protocols, and experience in regulated environments; AI-assisted tools and Linux command-line proficiency are valued additions.

As a Senior Software Technical Product Manager at Illumina, you will drive software design decisions for sequencing instrument platforms by translating user needs into product concepts and requirements. You'll collaborate with cross-functional teams (firmware, hardware, test) on release planning, backlog prioritization, and requirements management while creating wireframes, workflow diagrams, and formal specification documents.…See more The role requires deep involvement in use case development, competitive analysis, risk identification (FMEA, cybersecurity), and Voice of Customer advocacy across clinical, research, and applied segments. You'll manage scope and change control for multiple concurrent instrument development efforts while ensuring compliance with medical device regulations (IEC 62304, FDA guidance) and best practices in formalized requirements engineering.

Join Illumina's Primary Analysis team to design and develop high-performance signal processing software for genomic data analysis. You will architect C/C++ solutions for multi-threaded, real-time applications running on Linux, optimize algorithms for genomic base calling from image signals, and collaborate across bioinformatics, instrument design, and quality teams.…See more The role demands expertise in memory management, performance optimization, debugging tools, and unit testing, with 8+ years of professional software development experience.

Staff Software Engineer at Illumina's Primary Analysis team designing high-performance signal processing pipelines for genomic data analysis. The role involves architecting C/C++ software for multi-threaded, memory-optimized Linux applications that detect genomic signals from images, with responsibilities including algorithm development, performance optimization, debugging, and collaboration across bioinformatics, instrument design, and quality teams.…See more Requires 8+ years of professional software development experience, deep expertise in C/C++, multi-threading, memory management, and debugging/profiling tools, plus strong object-oriented design and unit testing practices.