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python jobs in San Diego

Posted 8 days ago

Automation QA Engineer for a genomics/bioinformatics project in San Diego. The role requires 3+ years of QA/test automation experience with Python, developing and maintaining automated test suites using pytest, unittest, or Robot Framework.… Responsibilities include functional, integration, and regression testing of genomics and sequencing software; validating NGS data and sample-to-result traceability; testing LIMS integrations and laboratory workflows; and collaborating with wet-lab and dry-lab teams to create real-world test scenarios. Knowledge of NGS, LIMS, bioinformatics, and life-sciences compliance is highly valuable.

San DiegoLast seen 6 days ago
$117,800 – $176,600 · Posted 8 days ago

Senior Embedded Software Engineer at Qualcomm's Data Center Business Unit, developing software and firmware for cloud edge and data center ML acceleration on high-performance silicon. The role requires deep embedded systems expertise including BSP, device driver development, RTOS, secure boot, TrustZone, and low-level peripheral interfaces (I2C/SPI/UART), combined with knowledge of ML frameworks and data movement optimization.… You will work on critical technologies like ML acceleration, in-memory processing, memory management, and virtualization across cross-functional international teams. Requires 2+ years of low-level C programming, proficiency with GNU/LLVM tools, embedded Linux, JTAG/SWD debugging, and multi-threaded SoC architecture understanding.

San DiegoLast seen 6 days ago
$129,500 – $194,300 · Posted 8 days ago

Senior software engineer role developing ADAS and autonomous driving software for Qualcomm's Snapdragon Ride platform. Responsibilities include designing sensor data acquisition systems (IMU, GPS, camera, radar, LiDAR), ensuring sensor synchronization, system-level benchmarking, and collaborating with vehicle integration teams.… Requires strong C++/C and Python proficiency, embedded systems experience, and expertise in safety-critical software development (ISO 26262, ASIL, ASPICE).

San DiegoLast seen 6 days ago
$175,000 – $185,000 · Posted 8 days ago

Principal Engineer leading the design, build, and operation of a Microsoft Fabric–based unified data platform (UDP) serving 50+ enterprise source systems across R&D, Commercial, Manufacturing, and Supply Chain. You will architect production-grade data ingestion pipelines, mentor data and analytics engineers, enforce engineering standards and SLAs, manage external implementation partners, and build the semantic layer and governance controls.… The role requires 10+ years of data engineering and platform architecture experience, 2+ years of technical leadership in a lakehouse environment, and deep hands-on expertise in Microsoft Fabric (lakehouses, Data Factory, deployment pipelines), PySpark, T-SQL, Python, medallion-architecture design, CI/CD, and data governance tooling—with biopharmaceutical or regulated-industry GxP experience strongly preferred.

San DiegoLast seen 6 days ago
$150,000 – $225,000 · Posted 8 days ago

Build production AI features and workflows powered by large language models, including retrieval-augmented generation (RAG), agentic orchestration, and tool/function calling integrations. You will design and implement scalable microservices in Python or Java that connect foundation model APIs to business data and internal systems, with responsibility for AI quality, evaluation, observability, and safe deployment on AWS.… Collaborate with cross-functional teams to prototype solutions, measure outcomes, and move proven capabilities into production while maintaining reliability, security, and auditability.

San DiegoLast seen 6 days ago
Posted 8 days ago

As an AI Quality Assurance Engineer, you will design and execute test automation for AI virtual assistants and cloud/on-premise bioscience software within the BIOVIA product suite. You will leverage ML/LLM systems knowledge, AI-assisted coding tools, and hands-on automation experience to reduce validation turnaround time and improve software release quality.… The role requires proficiency in Python, TypeScript, or JavaScript, familiarity with distributed test automation frameworks, and the ability to collaborate closely with development teams in a fast-paced, multi-threaded environment.

San DiegoLast seen 6 days ago
Posted 8 days ago

Design and optimize video analysis, quality assessment, and encoding algorithms for hardware-accelerated video codec solutions (FPGA/ASIC). Develop C-models and firmware implementing deep learning techniques (CNNs, Transformers, MLLMs) for video processing, ROI detection, and frame-level rate control.… Collaborate with infrastructure teams to integrate algorithms into production VOD and live-streaming pipelines, validate performance through A/B testing, and participate in objective video quality evaluation using metrics like VMAF, PSNR, and SSIM.

San DiegoLast seen 6 days ago
$90,000 – $184,000 · Posted 9 days ago

The Software Test Engineer will design, build, test, and deliver integrated software solutions for complex, mission-critical DoD systems. Responsibilities include testing software across mission systems, gathering requirements, developing test plans, and building/maintaining CI/CD pipelines for containerized deployments.… The role requires 3+ years of experience with version control, programming languages (C++, Python, Java, JavaScript), containers (Docker/OCI), SQL/relational databases, and Linux command-line usage, plus ability to work with modern frontend frameworks and DevSecOps practices.

San DiegoLast seen 8 days ago
$58,240 – $70,720 · Posted 9 days ago

This IT Security Engineer Intern role involves assessing software solutions for security vulnerabilities, providing feedback to developers on secure coding practices, and supporting deployment through secure DevSecOps pipelines. The intern will work with mission-focused engineers on DoD defense projects, gathering requirements, developing test plans, and integrating security scanning tools (SAST/DAST) into CI/CD workflows.… Required skills include application development in Java or C++ on Linux/Windows, familiarity with networking protocols, and understanding of OWASP Top 10 risks and DISA STIGs. The role emphasizes collaboration with software, systems, and integration engineers to deliver robust, cyber-secure technical solutions.

San DiegoLast seen 8 days ago
$70,000 – $100,000 · Posted 9 days ago

Develop, design, and execute tests for wireless features on macOS and Apple products, with focus on 802.11 MAC/PHY protocol validation. Maintain calibrated test beds, develop test plans and documentation, identify and isolate bugs using debugging tools, and automate test cases.… Requires 3+ years of wireless technology test engineering experience, deep knowledge of 802.11 and TCP/IP protocols, scripting proficiency, and hands-on use of network analysis tools.

San DiegoLast seen 6 days ago
$110,000 – $140,000 · Posted 9 days ago

System Administrator II responsible for provisioning, configuring, and sustaining AWS services (EC2, S3, VPC, Event Bridge) and on-premises infrastructure. The role requires developing Infrastructure as Code using Ansible, maintaining system patches per STIG compliance, scanning and remediating vulnerabilities with ACAS, and administrating Windows and Linux workstations and servers.… The candidate will support CI/CD workflows, monitor resources, and maintain comprehensive technical documentation while ensuring system architecture components integrate seamlessly.

San DiegoLast seen 6 days ago
$267,000 – $391,600 · Posted 9 days ago

Lead the scientific vision and execution of a generative AI platform for protein foundation models, starting with antibody and VHH design. You will build and manage a team of AI researchers and ML infrastructure engineers, define pretraining and post-training strategies across self-supervised learning, reinforcement learning, and transfer learning, and design confidence heads with out-of-distribution detection.… This is a founding role requiring deep expertise in structure-based generative modeling, multi-node GPU training, and the ability to shape cutting-edge computational approaches for therapeutic molecule discovery.

San DiegoLast seen 6 days ago
$117,800 – $176,600 · Posted 9 days ago

Senior Embedded Software Engineer role focused on designing and developing software/firmware for cloud edge and data center ML accelerators on Qualcomm silicon. The engineer will work on ML acceleration, memory management, virtualization, and board support packages (BSP), device drivers, RTOS, secure boot, and peripheral interfaces (PCIe, I2C/SPI/UART, DMA).… Requires 2+ years of low-level C programming on embedded platforms with proficiency in BSP development, device driver work, Embedded Linux, RTOS, and debugging tools (JTAG/SWD). Preferred experience includes ML frameworks (PyTorch, JAX), QuRT RTOS, and Qualcomm-specific middleware.

San DiegoLast seen 8 days ago
$168,000 – $268,400 · Posted 9 days ago

As an AI/ML advisor for biotherapeutics at Eli Lilly, you will lead training and fine-tuning experiments on proprietary infrastructure (LillyPod), curate and process biological data (sequences, structures, assays), and build evaluations that connect model outputs to experimental results. You will diagnose model failures, collaborate cross-functionally with protein scientists and wet-lab teams, and communicate findings to both computational and experimental audiences.… The role requires a Ph.D. in a quantitative field (or M.S. with 3+ years experience) and strong hands-on expertise in Python, PyTorch, and deep learning on GPUs, with preference for experience in geometric deep learning, protein language models, diffusion/flow-matching, and published ML applications to molecular data.

San DiegoLast seen 6 days ago
$89,440 – $133,120 · Posted 9 days ago

Designs and develops full-stack software for web applications and engineering tools, working across the data, integration, API, and UI layers. Writes reliable, testable, and maintainable code under supervision; completes technical tasks for system integrations, APIs, and software lifecycle pipelines.… Manages the development process from development through production release in collaboration with IT teams. Requires 2+ years of programming experience (Java, Python, etc.) and 1+ year with data structures, algorithms, and data stores.

San DiegoLast seen 6 days ago
$90,000 – $113,000 · Posted 9 days ago

Associate Software Engineer at Resmed will design, build, test, and deploy cloud-native applications and services that solve real healthcare customer problems. The role emphasizes modern software engineering practices, APIs, testing, and version control, with hands-on experience across the full development lifecycle from idea to production.… You'll use AI-assisted development tools and coding agents to support development and learning, and participate in code reviews, automated testing, CI/CD, and incident response. The position requires 2+ years of software development experience, strong programming fundamentals in a modern language, and genuine curiosity about how emerging AI-enabled engineering workflows can improve software development.

San DiegoLast seen 6 days ago
$120,000 – $140,000 · Posted 9 days ago

Senior Software Engineer responsible for architecting and developing scalable, high-performance backend applications and microservices using Python and Linux. You will design and operate containerized environments with Docker and Kubernetes, build automated CI/CD pipelines (GitLab CI/CD, Jenkins, or GitHub Actions), and integrate DevSecOps practices including container scanning and vulnerability remediation.… The role requires 7+ years of full-lifecycle software engineering experience, 5+ years with Docker/containerization, 3+ years with Kubernetes orchestration, and the ability to maintain an active Secret security clearance.

San DiegoLast seen 6 days ago
$58,240 – $70,720 · Posted 9 days ago

As a Software Test Engineer Intern, you will integrate and test software solutions across Innovative Defense Technologies' Integrated Mission Systems, working with developers, systems engineers, and subject matter experts to ensure high-quality, fully performing software. You will gather user requirements, define system functionality, and develop comprehensive test plans for applications written in Java, C++, Python, and JavaScript.… The role requires a strong foundation in application development with Java or C++ in Linux or Windows environments, along with the ability to provide actionable feedback to improve software quality and system integration.

San DiegoLast seen 8 days ago
$58,240 – $70,720 · Posted 9 days ago

This is a 10–12-week summer internship for software systems engineering students. Interns will contribute across the full software development lifecycle—from requirements analysis through deployment—creating and maintaining technical documentation while working on real-world problems.… The role expects familiarity with Git, Linux, SQL/PostgreSQL, and container technologies like Docker; experience with automation scripting (Python, Bash, PowerShell, Groovy), CI/CD pipelines, and DevSecOps is a strong plus.

San DiegoLast seen 8 days ago
Posted 9 days ago

Design, develop, and optimize algorithms for image and video compression (2D, multiview, 360-degree, point cloud, light field) across multiple formats and codecs. Research novel approaches to file formats, transport protocols, and quality evaluation metrics.… Participate in standardization bodies (MPEG, JVET, AVS, 3GPP) and publish findings in top-tier venues. Requires a PhD in computer science or related discipline, strong fundamentals in algorithms and data structures, published research record, and hands-on experience with video coding standards.

San DiegoLast seen 8 days ago
$114,000 – $171,000 · Posted 9 days ago

Principal Engineer Data will develop and execute a data architecture strategy aligned with business goals, building and maintaining data models, metadata standards, and integration frameworks. The role requires leading technical assessments for digitizing core business functions, working with stakeholders to translate requirements into architectural solutions, and ensuring data storage, retrieval, and governance meet enterprise standards.… The candidate must have a STEM degree with at least 5 years of experience (or Master's with 3 years), strong expertise in SQL Server, data visualization tools (Tableau, Power BI), and data architecture principles including data integration, governance, and security protocols.

San DiegoLast seen 6 days ago
$120,100 – $214,500 · Posted 9 days ago

Senior AI/ML Engineer responsible for shipping end-to-end production ML systems that enable autonomous medical coding in a SaaS platform. Will design robust ML architectures with low-latency inference, build reliable data and model pipelines using modern MLOps practices (CI/CD, model registries, experiment tracking), establish evaluation strategies with statistical rigor, and implement model observability and governance including drift detection and bias assessments.… Requires 5+ years of industry experience building and operating ML systems in production, 3+ years with C# or Python, 3+ years on Azure, and 1+ years of LLMOps expertise including prompt engineering and RAG.

San DiegoLast seen 9 days ago
$103,000 – $140,000 · Posted 9 days ago

San Diego County Credit Union is hiring three permanent Systems Engineers to lead enterprise infrastructure modernization across cloud, virtualization, storage, and automation. The role focuses on strategic engineering projects rather than help desk support, including VMware/enterprise virtualization administration, Windows Server/Active Directory management, Azure/AWS cloud environments, Pure Storage systems, infrastructure migrations, and PowerShell/Python/Bash automation.… Candidates should have experience with complex troubleshooting, root-cause analysis, identity management (Entra ID), backup/disaster recovery, and SaaS integrations in enterprise environments. The position offers Tier III/IV support responsibilities with dedicated NOC coverage handling operational tasks.

San DiegoLast seen 6 days ago
$77,600 – $176,000 · Posted 9 days ago

As an ML engineer at Booz Allen Hamilton, you'll design, build, and deploy production-grade AI/ML systems for Defense and Intelligence clients. You'll work across the full ML lifecycle—from model development in deep learning, computer vision, NLP, and signal processing through MLOps, containerization, and cloud deployment.… The role requires 2+ years of ML engineering or data science experience, proficiency with frameworks like TensorFlow and PyTorch, and the ability to obtain a Secret clearance.

San DiegoLast seen 8 days ago
$150,000 – $180,000 · Posted 10 days ago

Senior Bioinformatics Engineer responsible for designing, building, and operating production-grade, end-to-end bioinformatics pipelines that process and interpret large-scale genome cohorts. The role involves deep expertise in genome assembly, variant calling, structural-variant calling, haplotype phasing, and pangenome analysis, with the ability to select, adapt, and benchmark state-of-the-art algorithms.… Requires proficiency in Python and compiled languages (C++/Rust/Go), containerization (Docker/Singularity), workflow managers (Nextflow/Snakemake/WDL), and cloud environments (AWS/GCP). The position combines applied research—exploring AI approaches for biological insight—with continuous improvement of algorithms, code, and computational infrastructure, while mentoring junior staff in a startup environment.

San DiegoLast seen 8 days ago