Senior Bioinformatics Engineer responsible for designing, building, and operating production-grade, end-to-end bioinformatics pipelines that process and interpret large-scale genome cohorts. The role involves deep expertise in genome assembly, variant calling, structural-variant calling, haplotype phasing, and pangenome analysis, with the ability to select, adapt, and benchmark state-of-the-art algorithms.… Requires proficiency in Python and compiled languages (C++/Rust/Go), containerization (Docker/Singularity), workflow managers (Nextflow/Snakemake/WDL), and cloud environments (AWS/GCP). The position combines applied research—exploring AI approaches for biological insight—with continuous improvement of algorithms, code, and computational infrastructure, while mentoring junior staff in a startup environment.